मेडिकल काउन्सिल (NMCLE) – Medical Council (NMCLE) MCQ
मेडिकल काउन्सिल (NMCLE) – लाइसेन्स परीक्षा
Medical Council (NMCLE) · Nepal Professional License Exams · ५९१ प्रश्न
५९१ प्रश्न उपलब्ध। मोड छान्नुहोस्:
मेडिकल काउन्सिल (NMCLE): प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Proximal muscle weakness that improves with repeated effort, in a smoker with small cell lung cancer, suggests Lambert-Eaton syndrome, caused by antibodies against:
सही उत्तर: ख) Presynaptic voltage-gated calcium channels
Lambert-Eaton myasthenic syndrome is due to antibodies against presynaptic P/Q-type calcium channels, reducing acetylcholine release.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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After a difficult delivery with traction on the head, a newborn's arm hangs by the side, adducted and internally rotated with the forearm pronated ('waiter's tip'). The nerve roots injured are:
सही उत्तर: घ) C5 and C6 (Erb's palsy)
Erb's palsy results from upper brachial plexus (C5–C6) injury and produces the waiter's tip posture.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Facial palsy with painful vesicles in the external ear canal is called Ramsay Hunt syndrome and is caused by:
सही उत्तर: घ) Varicella-zoster virus reactivation in the geniculate ganglion
Ramsay Hunt syndrome is herpes zoster oticus involving the geniculate ganglion of the facial nerve.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Whipple's triad (symptoms of hypoglycaemia, low plasma glucose at that time and relief after glucose) is used to confirm:
सही उत्तर: क) A true hypoglycaemic disorder, such as insulinoma
Whipple's triad establishes genuine hypoglycaemia before searching for a cause such as insulinoma.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The earliest clinically detectable sign of diabetic nephropathy is:
सही उत्तर: ग) Moderately increased albuminuria (microalbuminuria)
A urine albumin excretion of about 30–300 mg/day is the earliest marker, appearing before any rise in creatinine.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Hyperpigmentation of the skin, palmar creases and buccal mucosa in primary adrenal insufficiency is due to:
सही उत्तर: ग) Raised ACTH and related pro-opiomelanocortin peptides
Loss of cortisol feedback raises ACTH, which is derived from POMC along with melanocyte-stimulating hormone, causing pigmentation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Multiple endocrine neoplasia type 2A comprises:
सही उत्तर: ग) Medullary thyroid carcinoma, phaeochromocytoma and parathyroid hyperplasia
MEN 2A (RET mutation) consists of medullary thyroid carcinoma, phaeochromocytoma and primary hyperparathyroidism.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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After a massive postpartum haemorrhage, a woman fails to lactate and later develops amenorrhoea and fatigue. The most likely diagnosis is:
सही उत्तर: ख) Sheehan's syndrome
Sheehan's syndrome is ischaemic necrosis of the enlarged pituitary after severe postpartum haemorrhage; failure of lactation is often the first sign.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Newborn screening for congenital hypothyroidism is usually done by measuring:
सही उत्तर: क) TSH in a heel-prick blood spot
A raised TSH on a heel-prick dried blood spot identifies congenital hypothyroidism, allowing early thyroxine treatment to prevent intellectual disability.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The antibodies most characteristic of Hashimoto's thyroiditis are directed against:
सही उत्तर: ख) Thyroid peroxidase (TPO)
High titres of anti-TPO (and anti-thyroglobulin) antibodies are typical of Hashimoto's thyroiditis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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