नेपाल व्यावसायिक लाइसेन्स नेपाल मेडिकल काउन्सिल लाइसेन्स (NMCLE) तयारी
नेपाल व्यावसायिक लाइसेन्स – नेपाल मेडिकल काउन्सिल लाइसेन्स (NMCLE)
NMC License Exam (NMCLE) · Nepal Professional License Exams
२,४१४ प्रश्न उपलब्ध। मोड छान्नुहोस्:
लाइसेन्स परीक्षा: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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In organophosphate poisoning, the drug given along with atropine to reactivate acetylcholinesterase, best given early before the enzyme 'ages', is:
सही उत्तर: ख) Pralidoxime
Oximes such as pralidoxime regenerate phosphorylated acetylcholinesterase if given before ageing occurs; atropine only blocks muscarinic effects.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In acute salicylate (aspirin) poisoning in an adult, the typical acid-base picture and a key treatment are:
सही उत्तर: क) Respiratory alkalosis with metabolic acidosis; urinary alkalinisation with sodium bicarbonate
Salicylates stimulate respiration and also cause metabolic acidosis; alkalinising the urine enhances salicylate excretion.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Aspirin is generally avoided in children with viral illnesses such as influenza or chickenpox because of the risk of:
सही उत्तर: ग) Reye's syndrome
Aspirin use during viral infections in children is associated with Reye's syndrome (acute encephalopathy with fatty liver).
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A child with abdominal colic, microcytic anaemia with basophilic stippling of red cells and a blue line on the gums most likely has poisoning with:
सही उत्तर: घ) Lead
Lead poisoning causes basophilic stippling, a Burtonian gum line, colic and neurotoxicity.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Numerous 'smudge cells' on the peripheral smear of an elderly patient with marked lymphocytosis suggest:
सही उत्तर: घ) Chronic lymphocytic leukaemia
Fragile CLL lymphocytes rupture during smear preparation, forming smudge cells.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A 'starry sky' appearance on histology and the translocation t(8;14) involving the MYC gene are characteristic of:
सही उत्तर: ग) Burkitt lymphoma
Burkitt lymphoma shows sheets of tumour cells with interspersed tingible-body macrophages and MYC translocation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The JAK2 V617F mutation is found in the large majority of patients with:
सही उत्तर: ख) Polycythaemia vera
About 95% of patients with polycythaemia vera carry the JAK2 V617F mutation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Increased osmotic fragility of red cells, spherocytes on the film and a family history of anaemia suggest:
सही उत्तर: ग) Hereditary spherocytosis
Spherocytes from membrane protein defects lyse more readily in hypotonic saline; splenectomy reduces haemolysis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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After eating fava beans or taking primaquine, a boy develops acute haemolysis; the blood film shows 'bite cells' and Heinz bodies. The likely diagnosis is:
सही उत्तर: घ) G6PD deficiency
Oxidant stress in G6PD deficiency denatures haemoglobin into Heinz bodies, which the spleen removes, leaving bite cells.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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To prevent vitamin K deficiency bleeding (haemorrhagic disease of the newborn), a term baby is given at birth:
सही उत्तर: घ) Vitamin K1 1 mg intramuscularly
A single 1 mg IM dose of phytomenadione at birth is the standard prophylaxis for term infants.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
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