फार्माकोलोजी – Pharmacology MCQ
फार्माकोलोजी – अन्तर्राष्ट्रिय नर्सिङ
Pharmacology · International Nursing (NCLEX-RN, DHA, HAAD) · ४०८ प्रश्न
४०८ प्रश्न उपलब्ध। मोड छान्नुहोस्:
फार्माकोलोजी: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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A client taking metoprolol (a beta-blocker) experiences shortness of breath and chest tightness. Which of the following is the *most* likely explanation for this reaction?
सही उत्तर: ग) C) Bronchospasm due to decreased beta-2 adrenergic receptor activity
Option C is correct. Metoprolol blocks beta-2 receptors, which are responsible for bronchodilation in the lungs. Blocking these receptors can lead to bronchoconstriction and symptoms like shortness of breath and chest tightness. Option A is less likely, option B is incorrect as metoprolol inhibits alpha receptors and option D is an unrelated condition.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In 2023, a client diagnosed with atrial fibrillation is started on warfarin for anticoagulation. Which laboratory value should the nurse monitor *most* closely to assess the patient’s risk of bleeding?
सही उत्तर: ख) B) Prothrombin Time (PT) / International Normalized Ratio (INR)
Option B is correct. The INR is a direct measure of the patient’s PT, which is key to assessing the anticoagulant effect of warfarin. Monitoring the PT/INR allows for precise dosage adjustments. Options A, C and D are not directly related to bleeding risk with warfarin.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A client taking isoniazid (INH) for tuberculosis has developed a persistently bitter taste in their mouth. This side effect is most commonly associated with which of the following?
सही उत्तर: घ) D) Mucosal irritation
Option D is correct. The bitter taste is a well-known and common side effect of INH, primarily due to its direct irritation of the mucous membranes in the mouth. Options A, B, and C are less frequently associated with INH administration. “
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A client with hypertension is prescribed amlodipine, a calcium channel blocker. The nurse understands that the primary mechanism of action for this drug involves which of the following?
सही उत्तर: क) A) Increasing heart rate and contractility
Option C is correct. Amlodipine’s primary action is vasodilatation via relaxation of vascular smooth muscle, lowering blood pressure. Options A and B are incorrect as amlodipine doesn't directly affect heart rate or beta receptors. Option D is incorrect as amlodipine does not stimulate aldosterone.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient requires intravenous administration of vancomycin. The nurse understands that monitoring for what laboratory test is crucial in preventing adverse reactions?
सही उत्तर: क) A) Complete Blood Count (CBC)
Option A is correct. Monitoring of the CBC, specifically neutrophil counts, during vancomycin administration is essential due to the drug's known propensity to cause neutropenic fever (a falsely elevated temperature). This often requires dose adjustments or alternative antibiotic therapy. The other options are not directly related to vancomycin-induced adverse reactions.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient with a history of asthma is being discharged home on montelukast (a leukotriene receptor antagonist). The nurse’s teaching regarding this medication should include:
सही उत्तर: ग) C) Reporting any rash or difficulty breathing immediately to the physician.
Option C is correct. Montelukast is used for asthma prevention and management. The key teaching point is to report any adverse reactions like rash or breathing difficulties, which are common side effects requiring medical attention. Option A is incorrect; B isn't appropriate due to long-term use potentially causing issues; and D may lead to overstimulation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A client with hypertension is taking lisinopril (a common ACE inhibitor). The nurse reviews the patient's laboratory results and notes a significantly elevated serum creatinine level. What is the MOST likely explanation for this finding?
सही उत्तर: ख) B) Decreased glomerular filtration rate due to ACE inhibition.
Option B is correct. Lisinopril, an ACE inhibitor, works by blocking the conversion of angiotensin I to angiotensin II, which reduces vasoconstriction and lowers blood pressure. This action can impair renal perfusion, leading to a decreased glomerular filtration rate (GFR) and elevated creatinine levels. Option A describes the intended effect; C represents another mechanism of action; and D is unrelated to ACE inhibitor use.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient is receiving morphine for pain management. The nurse observes cyanosis (bluish discoloration) of the lips and fingertips. Which of the following actions should the nurse take FIRST?
सही उत्तर: ख) B) Notify the physician immediately and document the observation.
Option B is correct. Cyanosis in a morphine-receiving patient indicates opioid-induced respiratory depression, a serious adverse effect. Immediate notification of the physician is paramount. Option A is contraindicated as it could worsen the respiratory depression. Elevating the legs would not address the underlying cause; and assessing only the rate and depth may be insufficient to recognize the severity.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient with chronic heart failure is prescribed furosemide (Lasix). Which of the following findings would MOST indicate that the dose is appropriate?
सही उत्तर: क) A) Decreased urine output and weight gain of 2 kg in 24 hours.
Option C is correct. Furosemide is a loop diuretic used to manage fluid overload in heart failure. The desired effect includes normalization of blood pressure, reduction of edema (swelling), and alleviation of shortness of breath – all reflected in the given symptoms. Option A represents excessive fluid retention and exacerbation of heart failure; B indicates electrolyte imbalance and poor hydration; and D shows adverse effects associated with fluid depletion.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A client is prescribed ranitidine for heartburn. Which statement correctly explains how this medication works?
सही उत्तर: ग) Blocks histamine receptors to reduce stomach acid production
Ranitidine is an H2-receptor antagonist that blocks histamine's action on parietal cells in the stomach, leading to decreased gastric acid secretion. The other options describe different mechanisms of action for other drugs used to treat heartburn.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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