चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) MD / MS / MDS प्रवेश परीक्षा तयारी
चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) – MD / MS / MDS प्रवेश परीक्षा
MECEE-PG – MD/MS/MDS · MECEE-PG (MD/MS/MDS)
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS/MDS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Pompe disease, which presents with cardiomegaly and hypotonia in infancy, is due to deficiency of:
सही उत्तर: क) Lysosomal acid α-1,4-glucosidase (acid maltase)
Pompe disease (type II) is a lysosomal glycogen storage disease that particularly affects heart and skeletal muscle.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A young man has muscle cramps and myoglobinuria on exercise, with no rise in blood lactate on ischaemic forearm exercise. The deficient enzyme is:
सही उत्तर: घ) Muscle glycogen phosphorylase (McArdle disease)
In McArdle disease (type V), muscle cannot break down glycogen during exercise, so lactate fails to rise and cramps with myoglobinuria follow.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Von Gierke disease (glycogen storage disease type I) is due to deficiency of:
सही उत्तर: क) Glucose-6-phosphatase
Glucose-6-phosphatase deficiency causes severe fasting hypoglycaemia, lactic acidosis, hepatomegaly and hyperuricaemia.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Vitamin C is essential for collagen synthesis because it is required for:
सही उत्तर: ग) Hydroxylation of proline and lysine residues
Prolyl and lysyl hydroxylases need ascorbate; defective hydroxylation produces unstable collagen and the features of scurvy.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Methylmalonic aciduria can result from deficiency of which vitamin, because it is a cofactor of methylmalonyl-CoA mutase?
सही उत्तर: ख) Vitamin B₁₂ (cobalamin)
Adenosylcobalamin is required by methylmalonyl-CoA mutase; B₁₂ deficiency raises methylmalonic acid, whereas folate deficiency raises homocysteine only.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following is an essential fatty acid for humans?
सही उत्तर: क) Linoleic acid
Humans cannot introduce double bonds beyond carbon 9, so linoleic (ω-6) and α-linolenic (ω-3) acids must come from the diet.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Long-chain fatty acids are transported into the mitochondria for β-oxidation with the help of:
सही उत्तर: ख) Carnitine
Carnitine (with carnitine palmitoyltransferase I and II) shuttles long-chain acyl groups across the inner mitochondrial membrane.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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On a Lineweaver–Burk (double reciprocal) plot, the intercept on the x-axis equals:
सही उत्तर: घ) −1/Km
The plot of 1/v against 1/[S] has a y-intercept of 1/Vmax, an x-intercept of −1/Km and a slope of Km/Vmax.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In competitive enzyme inhibition:
सही उत्तर: ग) Km increases while Vmax is unchanged
A competitive inhibitor competes for the active site; it can be overcome by excess substrate, so Vmax is unchanged but apparent Km rises.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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2,4-Dinitrophenol and thermogenin (UCP-1) of brown fat both act as:
सही उत्तर: क) Uncouplers of oxidative phosphorylation
Uncouplers dissipate the proton gradient across the inner mitochondrial membrane, so oxidation continues but energy is released as heat instead of ATP.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
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