चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) MD / MS / MDS प्रवेश परीक्षा तयारी
चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) – MD / MS / MDS प्रवेश परीक्षा
MECEE-PG – MD/MS/MDS · MECEE-PG (MD/MS/MDS)
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS/MDS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Which of the following statements BEST describes the mechanism by which azithromycin exerts its antibacterial effect? A) Inhibition of DNA gyrase. B) Interference with protein synthesis at the 50S ribosomal subunit. C) Blocking bacterial cell wall biosynthesis. D) Disruption of the bacterial cell membrane integrity.
सही उत्तर: ग) C) Blocking bacterial cell wall biosynthesis.
Azithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. The other options describe mechanisms used by different classes of antibiotics.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with severe diarrhea, fever, and abdominal cramps. Stool cultures reveal the presence of *Clostridium difficile* toxin. Which pharmacological intervention would be MOST appropriate as a primary treatment? A) Amoxicillin B) Metronidazole C) Ciprofloxacin D) Omeprazole
सही उत्तर: ख) B) Metronidazole
*Clostridium difficile* infection is typically treated with antibiotics like metronidazole, which specifically targets anaerobic bacteria. Amoxicillin is a penicillin and ineffective against *C. diff*, ciprofloxacin is a broad-spectrum antibiotic but doesn’t specifically target *C. diff*, and omeprazole is an anti-ulcer medication.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The presence of ‘ghost cells’ on a peripheral smear strongly suggests which pathological condition? A) Acute myeloid leukemia B) Chronic lymphocytic leukemia C) Autoimmune hemolytic anemia D) Thrombocytopenia
सही उत्तर: ग) C) Autoimmune hemolytic anemia
Ghost cells are characteristic of chronic lymphocytic leukemia (CLL), representing apoptotic lymphocytes that have not been fully phagocytosed. Acute myeloid leukemia presents with atypical blasts and autoimmune hemolytic anaemia involves red cell destruction, while thrombocytopenia is a deficiency of platelets.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following staining methods best demonstrates the granular structure and amyloid deposits within myocardial tissue? A) Wright’s stain B) Hematoxylin and Eosin (H&E) C) Crystal Violet stain D) Periodic Acid Schiff (PAS) stain
सही उत्तर: घ) D) Periodic Acid Schiff (PAS) stain
PAS stain is specifically designed to visualize carbohydrates and other staining substances like amyloid. H&E primarily stains cellular components with eosin and hematoxylin, providing general tissue morphology but not highlighting the granular aspects associated with amyloid deposits. Wright’s stain is used for stained blood smears and Crystal Violet stains are generally used in histology for specific stains such as collagen,
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In patients with chronic myeloid leukemia (CML), a key chromosomal abnormality involves translocation between chromosomes 9 and 22, resulting in which genetic alteration?
सही उत्तर: ग) Fusion of the BCR-ABL gene
Option 2, ‘Fusion of the BCR-ABL gene’, is correct. The Philadelphia chromosome results from a reciprocal translocation between chromosomes 9 and 22, creating a fusion gene (BCR-ABL) that encodes an abnormally active tyrosine kinase driving uncontrolled cell proliferation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The primary mechanism by which antibiotics like penicillin inhibit bacterial growth is through interference with:
सही उत्तर: घ) Protein translation
Option 3, ‘Cell wall biosynthesis’, is correct. Penicillins bind to enzymes involved in the peptidoglycan layer formation - a crucial component of bacterial cell walls – thus preventing bacteria from building their protective barriers. Options 1, 2, and 4 are incorrect as they relate to other cellular processes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the type of necrosis most commonly observed in myocardial infarction?
सही उत्तर: ख) Coagulative Necrosis
Option 1, ‘Coagulative Necrosis’, is correct. Myocardial infarction typically results in coagulative necrosis due to the interruption of blood supply and subsequent ischemia, leading to protein denaturation and tissue solidification. Liquefactive necrosis occurs due to enzymatic breakdown; caseous and fatty necroses are not typical of myocardial damage.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Loop diuretics like furosemide primarily affect which cellular process to reduce fluid volume?
सही उत्तर: ख) Sodium and chloride reabsorption
Option 1, ‘Sodium and chloride reabsorption’, is correct. Furosemide acts as a loop diuretic by inhibiting the Na-K-2Cl cotransporter in the loop of Henle, leading to increased excretion of sodium and chloride ions thus reducing fluid volume. The other options – protein synthesis, mitochondrial respiration, and cell adhesion – are not directly involved in the mechanism of action of loop diuretics.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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What does the term ‘Case Fatality Rate’ (CFR) represent in an infectious disease outbreak?
सही उत्तर: ग) C) The percentage of infected patients who die from the illness.
Option C is correct; CFR calculates the proportion of infected individuals who succumb to the disease. Options A, B, and D represent different epidemiological metrics related to infection spread or numbers.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A community health worker is conducting an assessment of malnutrition among children under five years old. Which of the following anthropometric measurements would be MOST crucial for identifying stunting?
सही उत्तर: ग) C) Height-for-Age Z-score.
Option C, the height-for-age z-score, is the most sensitive indicator of stunting (chronic malnutrition). The other options measure different aspects of nutritional status – MUAC assesses muscle mass, head circumference measures brain development, and weight-for-age Z-score gauges acute undernutrition.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
नमस्ते! पाठ्यक्रम, सामान्य ज्ञान, भाषा परीक्षा वा कुनै प्रश्नको उत्तर बुझ्न सोध्नुहोस्।
AI ले गल्ती गर्न सक्छ। महत्वपूर्ण कुरा आधिकारिक स्रोतमा जाँच्नुहोस्।