चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) MD / MS / MDS प्रवेश परीक्षा तयारी
चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) – MD / MS / MDS प्रवेश परीक्षा
MECEE-PG – MD/MS/MDS · MECEE-PG (MD/MS/MDS)
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS/MDS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Carbidopa is combined with levodopa in Parkinson disease because it:
सही उत्तर: क) Inhibits peripheral dopa decarboxylase
Carbidopa does not cross the blood-brain barrier, so it blocks peripheral conversion of levodopa to dopamine, allowing more levodopa to reach the brain and reducing nausea. Selegiline is the MAO-B inhibitor.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Gingival hyperplasia and hirsutism are characteristic adverse effects of:
सही उत्तर: ख) Phenytoin
Phenytoin causes gum hypertrophy, hirsutism, coarse facies and megaloblastic anaemia with long-term use. Valproate is associated with hepatotoxicity, weight gain and neural tube defects.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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An antithyroid drug that also inhibits peripheral conversion of T4 to T3 is:
सही उत्तर: घ) Propylthiouracil
Propylthiouracil inhibits thyroid peroxidase and peripheral 5'-deiodinase, so it is useful in thyroid storm; it is preferred in the first trimester of pregnancy. Its main risk is severe hepatotoxicity.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Sulfonylureas stimulate insulin release by:
सही उत्तर: घ) Closing ATP-sensitive K+ channels in pancreatic beta cells
Closing K-ATP channels depolarises the beta cell, opening calcium channels and causing insulin release; hypoglycaemia is the main risk. Metformin activates AMPK and pioglitazone acts on PPAR-gamma.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Low-dose aspirin produces its antiplatelet effect by:
सही उत्तर: ख) Irreversibly acetylating cyclooxygenase-1 in platelets
Aspirin irreversibly inhibits platelet COX-1, reducing thromboxane A2 for the life of the platelet (about 7-10 days), as platelets cannot make new enzyme. Clopidogrel acts by irreversibly blocking the P2Y12 receptor.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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An antiarrhythmic drug that can cause pulmonary fibrosis and both hypothyroidism and hyperthyroidism is:
सही उत्तर: क) Amiodarone
Amiodarone is iodine-rich and structurally similar to thyroxine, so it affects thyroid function; it also causes pulmonary fibrosis, corneal deposits and blue-grey skin. Thyroid, liver and lung function should be monitored.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Digoxin increases myocardial contractility by inhibiting:
सही उत्तर: घ) Na+/K+-ATPase
Inhibiting Na+/K+-ATPase raises intracellular Na+, which reduces Ca2+ removal by the Na+/Ca2+ exchanger and increases stored calcium for contraction. Milrinone, by contrast, inhibits phosphodiesterase III.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In organophosphate poisoning, pralidoxime acts by:
सही उत्तर: ग) Reactivating phosphorylated acetylcholinesterase
Pralidoxime removes the phosphate group from acetylcholinesterase if given before 'ageing' of the enzyme occurs. Atropine blocks muscarinic receptors but does not reverse the neuromuscular weakness.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A disulfiram-like reaction with alcohol is a well-known adverse effect of:
सही उत्तर: ख) Metronidazole
Metronidazole inhibits aldehyde dehydrogenase, so acetaldehyde builds up after alcohol, causing flushing, vomiting and headache. Patients should avoid alcohol during and for a short period after therapy.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Pyridoxine is given with isoniazid to prevent:
सही उत्तर: क) Peripheral neuropathy
Isoniazid increases pyridoxine excretion, leading to peripheral neuropathy, especially in malnourished, diabetic, alcoholic and HIV patients. Optic neuritis is caused by ethambutol and hyperuricaemia by pyrazinamide.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
नमस्ते! पाठ्यक्रम, सामान्य ज्ञान, भाषा परीक्षा वा कुनै प्रश्नको उत्तर बुझ्न सोध्नुहोस्।
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