चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) MD / MS / MDS प्रवेश परीक्षा तयारी
चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) – MD / MS / MDS प्रवेश परीक्षा
MECEE-PG – MD/MS/MDS · MECEE-PG (MD/MS/MDS)
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS/MDS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Negri bodies are diagnostic inclusion bodies of:
सही उत्तर: ग) Rabies
Negri bodies are eosinophilic intracytoplasmic inclusions in neurons, especially hippocampal pyramidal cells and cerebellar Purkinje cells, in rabies. Herpes simplex produces intranuclear Cowdry type A inclusions.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Barrett oesophagus is a recognised precursor of:
सही उत्तर: घ) Adenocarcinoma of the oesophagus
Barrett oesophagus is intestinal metaplasia (with goblet cells) of the lower oesophagus from chronic reflux, which can progress through dysplasia to adenocarcinoma. Squamous cell carcinoma is linked to smoking, alcohol and hot drinks.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Kimmelstiel-Wilson nodules are seen in:
सही उत्तर: क) Diabetic nephropathy
Nodular glomerulosclerosis with PAS-positive mesangial nodules (Kimmelstiel-Wilson lesion) is specific for diabetic nephropathy. Renal amyloid also expands the mesangium but stains with Congo red.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Effacement of podocyte foot processes on electron microscopy with normal light microscopy is characteristic of:
सही उत्तर: ग) Minimal change disease
Minimal change disease, the commonest cause of nephrotic syndrome in children, shows normal glomeruli on light microscopy and diffuse foot process effacement on EM. It responds well to corticosteroids.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Crescents in most glomeruli are the hallmark of:
सही उत्तर: घ) Rapidly progressive glomerulonephritis
Crescents form from proliferation of parietal epithelial cells and infiltrating macrophages in Bowman's space after severe glomerular injury. They define rapidly progressive (crescentic) GN, which can lead to renal failure within weeks.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The typical coagulation profile in haemophilia A is:
सही उत्तर: ग) Prolonged aPTT with normal PT and normal bleeding time
Factor VIII is part of the intrinsic pathway, so only aPTT is prolonged; platelet function and bleeding time are normal. An isolated prolonged PT suggests factor VII deficiency or early warfarin effect.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Paroxysmal nocturnal haemoglobinuria results from an acquired mutation in the PIGA gene, causing deficiency of:
सही उत्तर: क) GPI-anchored complement regulators CD55 and CD59
PIGA is needed to make the GPI anchor, so CD55 (DAF) and CD59 (MIRL) are absent and red cells are lysed by complement. Flow cytometry for CD55/CD59 is the diagnostic test; C1 inhibitor deficiency causes hereditary angioedema.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Heinz bodies and 'bite cells' after taking an oxidant drug suggest:
सही उत्तर: ग) G6PD deficiency
G6PD deficiency reduces NADPH, so oxidant stress denatures haemoglobin into Heinz bodies, which splenic macrophages remove, leaving bite cells. Drugs such as primaquine and dapsone commonly precipitate haemolysis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In sickle cell disease, the mutation in the beta-globin chain replaces glutamic acid at position 6 with:
सही उत्तर: ख) Valine
HbS results from a point mutation substituting valine for glutamic acid at position 6, causing polymerisation when deoxygenated. Substitution by lysine at the same position produces HbC.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which laboratory finding is typical of iron deficiency anaemia?
सही उत्तर: ख) Increased total iron-binding capacity
In iron deficiency, the liver makes more transferrin, so TIBC rises while ferritin and transferrin saturation fall. RDW is increased because of variation in red cell size.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
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