मेडिसिन – Medicine MCQ
मेडिसिन – MD/MS प्रवेश
Medicine · MECEE-PG – MD/MS/MDS Entrance · ५४२ प्रश्न
५४२ प्रश्न उपलब्ध। मोड छान्नुहोस्:
मेडिसिन: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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For primary prophylaxis of variceal bleeding in cirrhosis with large varices, the commonly used drug is:
सही उत्तर: क) Propranolol
Non-selective beta-blockers such as propranolol or carvedilol reduce portal pressure and prevent first bleeding. Octreotide and terlipressin are used in acute variceal bleeding, not long-term prophylaxis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Hypercalcaemia due to PTH-related peptide is most typically associated with which lung cancer?
सही उत्तर: घ) Squamous cell carcinoma
Squamous cell carcinoma of the lung commonly secretes PTHrP, causing humoral hypercalcaemia of malignancy. Small cell carcinoma is associated with SIADH and ectopic ACTH.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Bence Jones proteinuria, punched-out lytic skull lesions and rouleaux formation suggest:
सही उत्तर: ग) Multiple myeloma
Multiple myeloma is a plasma cell malignancy producing monoclonal light chains (Bence Jones proteins) and osteolytic lesions. Prostate cancer metastases are typically osteoblastic (sclerotic).
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Hypoglycaemia with a high serum insulin but low C-peptide level suggests:
सही उत्तर: ख) Exogenous insulin administration
Commercial insulin lacks C-peptide, so exogenous insulin raises insulin but suppresses endogenous C-peptide. Insulinoma and sulfonylureas raise both insulin and C-peptide.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The main specific antidote used in organophosphate poisoning to reverse muscarinic effects is:
सही उत्तर: क) Atropine
Organophosphates inhibit acetylcholinesterase; atropine blocks the resulting muscarinic overactivity and is titrated to dry chest secretions. Physostigmine is itself a cholinesterase inhibitor and would worsen toxicity.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In people living with HIV, cotrimoxazole prophylaxis against Pneumocystis pneumonia is indicated when the CD4 count falls below:
सही उत्तर: घ) 200 cells/µL
A CD4 count below 200 cells/µL markedly increases the risk of Pneumocystis jirovecii pneumonia. A CD4 below 50 is the threshold for Mycobacterium avium complex risk.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The drug of choice for severe falciparum malaria in adults is:
सही उत्तर: ग) Intravenous artesunate
IV artesunate reduces mortality compared with quinine and is the WHO-recommended first-line treatment for severe malaria. Primaquine is used for radical cure of vivax malaria and as a gametocidal agent.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A febrile patient with an eschar and lymphadenopathy is suspected to have scrub typhus. The drug of choice is:
सही उत्तर: ख) Doxycycline
Scrub typhus (Orientia tsutsugamushi) responds to doxycycline; azithromycin is an alternative in pregnancy. Beta-lactams are ineffective against this intracellular organism.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Visceral leishmaniasis (kala-azar) is transmitted by:
सही उत्तर: क) Phlebotomus sandfly
Leishmania donovani is transmitted by the female Phlebotomus sandfly. Reduviid bugs transmit Chagas disease and tsetse flies transmit African sleeping sickness.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The vector of Japanese encephalitis is:
सही उत्तर: घ) Culex mosquito
Japanese encephalitis virus is transmitted by Culex mosquitoes (e.g. Culex tritaeniorhynchus) with pigs as amplifying hosts. Aedes transmits dengue.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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