मेडिसिन – Medicine MCQ
मेडिसिन – MD/MS प्रवेश
Medicine · MECEE-PG – MD/MS/MDS Entrance · ५४२ प्रश्न
५४२ प्रश्न उपलब्ध। मोड छान्नुहोस्:
मेडिसिन: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Type 1 autoimmune hepatitis is characteristically associated with which autoantibodies?
सही उत्तर: घ) Antinuclear and anti-smooth muscle antibodies
Type 1 AIH (the commoner form) shows ANA and anti-smooth muscle (anti-actin) antibodies with raised IgG; type 2 has anti-LKM-1.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In chronic hepatitis B, the presence of HBeAg indicates:
सही उत्तर: ग) Active viral replication and high infectivity
HBeAg is a marker of active replication; its loss with seroconversion to anti-HBe usually signals lower viral replication.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In the serological diagnosis of hepatitis B, the marker detectable during the 'window period' (after HBsAg disappears and before anti-HBs appears) is:
सही उत्तर: क) IgM anti-HBc
During the window period only antibody to the core antigen (IgM anti-HBc) is detectable, so it may be the sole marker of recent infection.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Hypercalcaemia due to secretion of PTH-related peptide is most typical of which type of lung cancer?
सही उत्तर: ख) Squamous cell carcinoma
Squamous cell carcinoma of the lung commonly secretes PTHrP, causing humoral hypercalcaemia of malignancy; small cell carcinoma is associated with SIADH and ACTH.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Clubbing, painful swelling of the wrists and ankles and periosteal new bone formation on X-ray in a smoker suggest:
सही उत्तर: घ) Hypertrophic pulmonary osteoarthropathy due to lung cancer
Hypertrophic pulmonary osteoarthropathy, most often with non-small cell lung cancer, causes clubbing, arthralgia and periostitis of long bones.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Type 2 (hypercapnic) respiratory failure is defined by hypoxaemia together with:
सही उत्तर: ग) Raised PaCO₂ (above about 50 mmHg)
Type 1 failure is hypoxaemia with normal or low PaCO₂; type 2 adds hypercapnia, reflecting alveolar hypoventilation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The diffusing capacity for carbon monoxide (DLCO) is characteristically INCREASED in:
सही उत्तर: घ) Diffuse alveolar haemorrhage
Blood in the alveoli binds CO, raising DLCO; it also rises in polycythaemia and asthma, whereas emphysema, fibrosis and pulmonary vascular disease reduce it.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In restrictive lung disease such as pulmonary fibrosis, spirometry typically shows:
सही उत्तर: ख) Reduced FVC with normal or raised FEV1/FVC ratio
Restriction reduces lung volumes proportionately (FEV1 and FVC both fall), so the ratio is preserved or high; obstruction lowers the ratio.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Digital clubbing is NOT a typical feature of:
सही उत्तर: ग) Uncomplicated chronic obstructive pulmonary disease
Clubbing occurs in suppurative lung disease, fibrosis and lung cancer; its presence in COPD should prompt a search for another cause such as malignancy.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The hallmark of hypertrophic cardiomyopathy on echocardiography is:
सही उत्तर: क) Asymmetric septal hypertrophy
HCM typically shows asymmetric hypertrophy of the interventricular septum, often with systolic anterior motion of the mitral valve.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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