स्नातकोत्तर मेडिकल प्रवेश (MECEE-PG)
स्नातकोत्तर मेडिकल प्रवेश (MECEE-PG)
MECEE-PG – MD/MS/MDS Entrance · २,८६५ प्रश्न
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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The mechanism by which Linezolid inhibits bacterial protein synthesis differs from that of tetracycline antibiotics. Specifically, Linezolid acts by: a) Preventing tRNA binding to ribosomes. b) Inhibiting 30S ribosomal subunit translocation. c) Blocking the formation of the initiation complex. d) Disrupting the integrity of the bacterial cell wall.
सही उत्तर: ख) b) Inhibiting 30S ribosomal subunit translocation
Linezolid is a specific inhibitor of bacterial protein synthesis by binding to the 80S ribosome and preventing the dissociation of the peptidyl-tRNA from the ribosome. This mechanism differs fundamentally from tetracyclines which target tRNA binding. The other options represent common mechanisms of action for various antibiotics.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Epithelioid cells are most commonly seen in granulomas formed by the immune response to which of the following pathogens? a) *Mycobacterium tuberculosis* b) *Streptococcus pneumoniae* c) *Candida albicans* d) *Enterococcus faecalis*
सही उत्तर: क) a) *Mycobacterium tuberculosis*
Epithelioid cells are histiocytes that differentiate in response to chronic inflammation and are heavily involved in the defense against intracellular pathogens like *Mycobacterium tuberculosis*. The other options represent extracellular bacteria or fungi which don’t typically induce this type of cellular differentiation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with symptoms including fever, headache, and stiff neck. CSF analysis reveals numerous neutrophils and cryptococcal polysaccharide antigens. Which fungal pathogen is most likely responsible for this clinical presentation?
सही उत्तर: ग) *Cryptococcus neoformans*
The combination of neurological symptoms, CSF findings (neutrophils and cryptococcal antigens), strongly suggests infection with *Cryptococcus neoformans*. *Candida*, *Aspergillus,* and *Mucor* species are less likely given this clinical profile. This was consistent with 2080 data.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A biopsy specimen from a patient diagnosed with tuberculosis shows the presence of multinucleated giant cells engulfing macrophages and cellular debris. Which characteristic is MOST indicative of this finding?
सही उत्तर: क) Granuloma formation
The hallmark of granulomatous disease, such as tuberculosis, is the presence of multinucleated giant cells (formed from fusion of macrophages). The other options represent different inflammatory responses. This finding was consistent with 2078 observations.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with severe diarrhea, abdominal cramps, and fever following antibiotic treatment with ampicillin. Microscopic examination of the stool reveals numerous motile flagellated bacteria. The most likely causative agent is:
सही उत्तर: ग) *Shigella dysenteriae*
*Salmonella enterica* is a common cause of bacterial diarrhea, particularly in the setting of antibiotic use. While *E. coli* and *Shigella* can also cause diarrhea, the presence of motile flagellated bacteria points toward *Salmonella*. *Clostridium difficile* typically causes pseudomembranous colitis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following immunological mechanisms is primarily associated with the development of erythema multiforme due to *Clostridium difficile* infection?
सही उत्तर: घ) Type IV Hypersensitivity
Type IV hypersensitivity (Cell-mediated) is characterized by delayed reactions involving T cells, which aligns with the characteristic skin lesions of *C. difficile*-induced colitis. Type I involves IgE and mast cell activation, Type II antibody-antigen complexes, and Type III immune complex mediated inflammation are incorrect.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The concept of ‘reproductive health’ encompasses which of the following elements?
सही उत्तर: ग) C. Immunization programs for children under five years.
Option 2 is correct as reproductive health encompasses a wide range of services related to women's health, including prenatal, delivery, and postpartum care alongside family planning choices. Options A, C, and D represent specific aspects but do not fully capture the broader scope of reproductive health.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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What is the primary purpose of conducting a Sentinel Surveillance system in Nepal?
सही उत्तर: ग) C. To provide detailed clinical information about every patient diagnosed with a communicable disease.
Option 2 is correct; Sentinel surveillance involves monitoring key diseases from a subset of healthcare facilities, allowing for early detection and rapid response to outbreaks without overwhelming resources. Options A, C and D describe broader aspects of disease monitoring but don’t capture the focused nature of sentinel systems.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A public health worker is investigating a cluster of diarrheal cases in a rural community. Which epidemiological study design would be most appropriate to determine the potential source of contamination?
सही उत्तर: ख) B. Case-control study comparing individuals with the disease to a control group without it.
Option 1 is correct because a case-control design allows for efficient comparison of exposure histories between cases (individuals with the disease) and controls (those without), facilitating identification of potential risk factors. Options A and C require more extensive data collection and follow-up, while Option D involves intervention assessment not source investigation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The term ‘Z score’ is most appropriately used in Community Medicine to represent:
सही उत्तर: ग) C. The number of standard deviations a particular data point is from the mean.
Option C is correct as Z-scores are statistical measures that quantify relative position in a dataset, indicating how many standard deviations a value differs from the mean, which is crucial for understanding disease prevalence and variation across populations. Options A and B use terms not typically associated with Z-scores and Option D describes incidence rates.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
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