चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) MD / MS / MDS प्रवेश परीक्षा तयारी
चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) – MD / MS / MDS प्रवेश परीक्षा
MECEE-PG – MD/MS/MDS · MECEE-PG (MD/MS/MDS)
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS/MDS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
-
Aminoglycosides inhibit bacterial protein synthesis by binding to the:
सही उत्तर: ख) 30S ribosomal subunit
Aminoglycosides bind the 30S subunit, causing misreading of mRNA, and are bactericidal. Macrolides, chloramphenicol, clindamycin and linezolid act on the 50S subunit.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
'Red man syndrome' with flushing of the upper body is associated with rapid intravenous infusion of:
सही उत्तर: घ) Vancomycin
Rapid vancomycin infusion causes non-immunological histamine release; it is prevented by slow infusion over at least an hour. Rifampicin causes orange-red discolouration of body fluids, not flushing.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Which of the following is a potent inducer of hepatic microsomal (CYP450) enzymes?
सही उत्तर: क) Rifampicin
Rifampicin strongly induces CYP3A4 and other enzymes, reducing levels of oral contraceptives, warfarin and many antiretrovirals. Cimetidine, ketoconazole and erythromycin are enzyme inhibitors.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
A drug has a volume of distribution of 40 L and a desired plasma concentration of 2 mg/L. With 100% bioavailability, the loading dose is:
सही उत्तर: ख) 80 mg
Loading dose = Vd × target concentration / F = 40 L × 2 mg/L / 1 = 80 mg. The loading dose depends on volume of distribution, whereas the maintenance dose depends on clearance.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
A patient is given 200 mg of a drug with a half-life of 6 hours. Assuming first-order elimination, how much remains in the body after 24 hours?
सही उत्तर: घ) 12.5 mg
24 hours equals 4 half-lives, so 200 → 100 → 50 → 25 → 12.5 mg. 25 mg would be the amount after only 3 half-lives (18 hours).
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Which of the following drugs follows zero-order elimination kinetics at usual doses?
सही उत्तर: ख) Ethanol
Alcohol dehydrogenase is saturated at usual blood alcohol levels, so a fixed amount is removed per hour (zero order). Phenytoin and high-dose aspirin also shift to zero-order kinetics.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
The Arthus reaction is an example of which type of hypersensitivity?
सही उत्तर: ग) Type III
The Arthus reaction is a localised immune-complex vasculitis at the injection site, a type III reaction. Type IV is delayed, T-cell mediated hypersensitivity.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Toxic shock syndrome toxin-1 (TSST-1) of Staphylococcus aureus acts as a:
सही उत्तर: घ) Superantigen
Superantigens bind MHC class II and the T-cell receptor outside the antigen groove, activating many T cells and causing a massive cytokine release. SNARE protein cleavage is the mechanism of tetanus and botulinum toxins.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
The toxic component of the lipopolysaccharide (endotoxin) of Gram-negative bacteria is:
सही उत्तर: क) Lipid A
Lipid A triggers macrophages via TLR4 to release cytokines, causing fever and septic shock. The O polysaccharide is the antigenic part; teichoic acid is found in Gram-positive walls.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
The standard conditions for sterilisation in an autoclave are:
सही उत्तर: घ) 121°C for 15 minutes at 15 lb/in² pressure
Moist heat under pressure at 121°C for 15 minutes kills spores. 160°C for 2 hours is the hot-air oven, 100°C on three days is tyndallisation and 63°C for 30 minutes is holder pasteurisation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
नमस्ते! पाठ्यक्रम, सामान्य ज्ञान, भाषा परीक्षा वा कुनै प्रश्नको उत्तर बुझ्न सोध्नुहोस्।
AI ले गल्ती गर्न सक्छ। महत्वपूर्ण कुरा आधिकारिक स्रोतमा जाँच्नुहोस्।