चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) MD / MS / MDS प्रवेश परीक्षा तयारी
चिकित्सा स्नातकोत्तर प्रवेश (MECEE-PG) – MD / MS / MDS प्रवेश परीक्षा
MECEE-PG – MD/MS/MDS · MECEE-PG (MD/MS/MDS)
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS/MDS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Which laboratory finding is characteristic of Wilson's disease?
सही उत्तर: क) Low serum ceruloplasmin
Mutation of the ATP7B copper transporter impairs incorporation of copper into ceruloplasmin and biliary excretion, so serum ceruloplasmin falls while urinary and hepatic copper rise. Kayser–Fleischer rings in the cornea are a classic sign.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A double-stranded DNA sample contains 20% adenine. What is its cytosine content?
सही उत्तर: ख) 30%
By Chargaff's rule A = T and G = C, so A + T = 40% and G + C = 60%, giving cytosine = 30%. Choosing 20% wrongly equates cytosine with adenine.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following codons is a stop (termination) codon?
सही उत्तर: ख) UGA
The three stop codons are UAA, UAG and UGA. AUG is the start codon (methionine) and UGG codes for tryptophan.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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During DNA replication, Okazaki fragments are formed on the:
सही उत्तर: ग) Lagging strand
The lagging strand is synthesised discontinuously in short 5'→3' pieces (Okazaki fragments), each started by an RNA primer and later joined by DNA ligase. The leading strand is synthesised continuously toward the replication fork.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Long-chain fatty acids are transported into the mitochondrial matrix for beta-oxidation with the help of:
सही उत्तर: क) Carnitine
Carnitine palmitoyltransferase I forms acylcarnitine, which crosses the inner mitochondrial membrane; CPT-I is inhibited by malonyl-CoA. Albumin carries free fatty acids in plasma, not across mitochondrial membranes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The liver cannot utilise ketone bodies because it lacks the enzyme:
सही उत्तर: घ) Succinyl-CoA:acetoacetate CoA transferase (thiophorase)
Thiophorase activates acetoacetate to acetoacetyl-CoA in extrahepatic tissues; its absence in liver ensures ketone bodies are exported. HMG-CoA synthase and lyase are present in liver because they make ketone bodies.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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An enzyme has Vmax = 100 µmol/min and Km = 2 mM. At a substrate concentration of 6 mM, the reaction velocity is:
सही उत्तर: ख) 75 µmol/min
By the Michaelis–Menten equation, v = Vmax[S]/(Km + [S]) = 100 × 6/(2 + 6) = 75 µmol/min. Velocity equals half of Vmax (50) only when [S] equals Km.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A competitive inhibitor of an enzyme causes:
सही उत्तर: क) Increased apparent Km with unchanged Vmax
A competitive inhibitor competes for the active site, so more substrate is needed for half-maximal velocity (higher Km), but very high substrate overcomes it (Vmax unchanged). Non-competitive inhibitors lower Vmax without changing Km.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Cyanide poisoning blocks the electron transport chain by inhibiting:
सही उत्तर: क) Complex IV (cytochrome c oxidase)
Cyanide binds the ferric iron of cytochrome a3 in complex IV, stopping oxygen use despite adequate oxygen delivery; carbon monoxide also inhibits complex IV. Oligomycin inhibits complex V and rotenone inhibits complex I.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The enzyme catalysing the rate-limiting step of the hexose monophosphate (pentose phosphate) shunt is:
सही उत्तर: क) Glucose-6-phosphate dehydrogenase
G6PD produces NADPH, which keeps glutathione reduced and protects RBCs from oxidative damage; its deficiency causes haemolysis after oxidant drugs or fava beans. Transketolase, a thiamine-dependent enzyme, acts in the non-oxidative phase.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
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