स्नातकोत्तर मेडिकल प्रवेश (MECEE-PG)
स्नातकोत्तर मेडिकल प्रवेश (MECEE-PG)
MECEE-PG – MD/MS/MDS Entrance · २,८६५ प्रश्न
२,८६५ प्रश्न उपलब्ध। मोड छान्नुहोस्:
MD/MS प्रवेश: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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A patient presents with severe hypotension, disseminated intravascular coagulation (DIC), and evidence of acute renal failure following a recent insect bite. Histopathological examination reveals the presence of ‘Aschoff bodies’ within the affected tissues. Which of the following conditions is most likely being diagnosed?
सही उत्तर: क) _Rocky Mountain Spotted Fever
'Aschoff bodies' (Anitschkow bodies) are pathognomonic for Lyme disease, particularly in cases involving disseminated infection and associated complications like DIC and renal failure. The insect bite provides a clue to the etiology of the illness. The other conditions could cause DIC but lack this specific histological feature.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The presence of ‘ground glass’ opacity on chest CT scans is most commonly associated with which of the following infectious diseases?
सही उत्तर: ग) _Legionella pneumophila
_Legionella pneumophila_ (Legionnaires' disease) often presents with ground glass opacities on chest CT scans, reflecting alveolar damage and inflammation. _M_. _pneumoniae_ and _C._ _pneumoniae_ are primarily associated with atypical pneumonia presenting differently, while influenza typically causes consolidation. This question is designed to test knowledge of a specific radiological finding linked to an infection.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the pathogenesis of disseminated intravascular coagulation (DIC)?
सही उत्तर: ख) _A systemic activation of the coagulation cascade leading to widespread microthrombosis and consumption of clotting factors._
DIC is characterized by a systemic activation of the coagulation cascade followed by the consumption of clotting factors. This leads to microthrombosis and subsequent bleeding diathesis. Option 1 describes inflammation, option 2 is partially correct but misses the key factor of consumption, and option 3 relates to vitamin K deficiency which primarily affects clot synthesis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with symptoms consistent with pneumonia. Microscopic examination of a sputum sample reveals numerous gram-negative bacilli, many intracellular, along with inflammatory cells. Which of the following organisms is MOST likely responsible for this infection?
सही उत्तर: क) _Klebsiella pneumoniae
_Klebsiella pneumoniae_ is a common cause of pneumonia, often presenting with similar findings in sputum samples due to its ability to survive and multiply intracellularly. The other options are less likely given the typical presentation described – _S. aureus_ typically causes cellulitis, _E. coli_ urinary tract infections, and _P. aeruginosa_ opportunistic infections.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following clinical manifestations is MOST strongly associated with disseminated intravascular coagulation (DIC) in a patient with sepsis?
सही उत्तर: ख) Thrombocytosis accompanied by microangiopathic hemolytic anemia
DIC is characterized by widespread activation of the coagulation cascade, leading to consumption of platelets and formation of fibrin clots. The presence of microangiopathic hemolytic anemia (MAHA) – fragmented red blood cells - is a hallmark of this condition. The other options describe alternative coagulopathies.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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What is the primary mechanism of action of penicillin G against bacteria?
सही उत्तर: ग) Interference with protein translation
Penicillin G inhibits bacterial cell wall synthesis by binding to transpeptidases, enzymes crucial for cross-linking peptidoglycans – a vital component of the bacterial cell wall. This weakens the cell wall and ultimately leads to bacterial death. The other options represent different mechanisms of action for antibiotics.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which histological feature would you MOST likely find associated with a diagnosis of ‘atypical hyperplasia’ in breast tissue?
सही उत्तर: ग) Complete cellular differentiation resembling normal epithelium
Atypical hyperplasia is characterized by abnormal cells exhibiting nuclear features such as pleomorphism (variation in size and shape) and an increased mitotic rate. These findings suggest a potential for progression to malignancy. The other options represent more benign or well-differentiated breast tissue alterations.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following biochemical alterations is MOST commonly observed in patients suffering from chronic obstructive pulmonary disease (COPD)?
सही उत्तर: ग) Elevated red blood cell count
Patients with COPD frequently exhibit decreased arterial oxygen tension due to impaired alveolar-capillary diffusion and reduced lung compliance. This reflects the underlying damage to the respiratory system. The other options are not typically primary features of COPD pathology.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The presence of ‘coffee ground’ appearance in vomit is MOST indicative of damage to which structure?
सही उत्तर: घ) Stomach
A ‘coffee ground’ appearance in vomitus typically signifies the presence of digested blood resulting from mucosal erosion or ulceration within the jejunum. The jejunum is a highly absorptive region and therefore susceptible to damage leading to bleeding. While all listed areas can experience bleeding, the jejunum's location makes this presentation most characteristic.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following cellular processes is MOST directly associated with the development of granulomas in conditions like tuberculosis?
सही उत्तर: ख) Macrophage activation and antigen presentation
Granulomas are collections of immune cells that form as a response to persistent infections or inflammation. Macrophage activation and subsequent antigen presentation are key steps in this process, leading to the formation of granuloma structures. The other options represent different cellular functions without direct relevance to granuloma formation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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