मेडिसिन – Medicine MCQ
मेडिसिन – MD/MS प्रवेश
Medicine · MECEE-PG – MD/MS/MDS Entrance · ५४२ प्रश्न
५४२ प्रश्न उपलब्ध। मोड छान्नुहोस्:
मेडिसिन: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Antimitochondrial antibody is the serological hallmark of:
सही उत्तर: ग) Primary biliary cholangitis
Antimitochondrial antibodies are positive in about 95% of primary biliary cholangitis, typically in middle-aged women. Autoimmune hepatitis type 1 is associated with anti-smooth muscle and antinuclear antibodies.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The only serological marker that may be positive during the 'window period' of acute hepatitis B is:
सही उत्तर: ख) IgM anti-HBc
In the window period HBsAg has disappeared but anti-HBs is not yet detectable, so IgM anti-HBc is the marker of recent infection. Anti-HBs alone indicates immunity, e.g. after vaccination.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Kayser–Fleischer rings and low serum ceruloplasmin are characteristic of:
सही उत्तर: क) Wilson disease
Wilson disease is an autosomal recessive disorder of copper excretion (ATP7B) with copper deposition in Descemet membrane. Haemochromatosis is iron overload with high ferritin and transferrin saturation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The most common cause of hypercalcaemia in ambulatory (outpatient) patients is:
सही उत्तर: घ) Primary hyperparathyroidism
Primary hyperparathyroidism, usually from a single parathyroid adenoma, is the commonest cause in outpatients. Malignancy is the commonest cause among hospitalised patients.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The treatment of choice for central diabetes insipidus is:
सही उत्तर: ग) Desmopressin
Desmopressin is a synthetic ADH analogue that replaces the deficient hormone in central DI. Thiazides are used for nephrogenic DI, and demeclocycline/tolvaptan are used for SIADH.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The best single screening test for acromegaly is:
सही उत्तर: ख) Serum IGF-1
IGF-1 reflects integrated GH secretion and is the best screening test; diagnosis is confirmed by failure of GH suppression on an oral glucose tolerance test. Random GH is unreliable because GH is secreted in pulses.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The preferred initial biochemical test for suspected phaeochromocytoma is:
सही उत्तर: क) Plasma free metanephrines
Plasma free (or urinary fractionated) metanephrines are the most sensitive screening tests for phaeochromocytoma. Urinary 5-HIAA is used for carcinoid tumours.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Hypertension with hypokalaemia, low plasma renin and high aldosterone suggests:
सही उत्तर: घ) Primary hyperaldosteronism
Primary hyperaldosteronism (Conn syndrome) has autonomous aldosterone secretion suppressing renin. Renal artery stenosis causes secondary hyperaldosteronism with high renin.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The typical electrolyte abnormality in primary adrenal insufficiency (Addison disease) is:
सही उत्तर: ग) Hyponatraemia with hyperkalaemia
Loss of aldosterone causes sodium wasting and potassium retention in Addison disease. Hypernatraemia with hypokalaemia suggests mineralocorticoid excess such as Conn syndrome.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The antithyroid drug preferred during the first trimester of pregnancy is:
सही उत्तर: ख) Propylthiouracil
Propylthiouracil is preferred in the first trimester because carbimazole/methimazole are associated with embryopathy (e.g. aplasia cutis). Radioactive iodine is contraindicated in pregnancy.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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