प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – Pathology, Microbiology & Pharmacology MCQ
प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – MD/MS प्रवेश
Pathology, Microbiology & Pharmacology · MECEE-PG – MD/MS/MDS Entrance · ४०८ प्रश्न
४०८ प्रश्न उपलब्ध। मोड छान्नुहोस्:
प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
-
Linezolid inhibits bacterial protein synthesis by:
सही उत्तर: घ) Preventing formation of the 70S initiation complex
Linezolid (an oxazolidinone) binds the 50S subunit's 23S rRNA and blocks formation of the initiation complex, so cross-resistance with other classes is rare.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Patients taking metronidazole are advised to avoid alcohol because of the risk of:
सही उत्तर: ग) A disulfiram-like reaction
Metronidazole inhibits aldehyde dehydrogenase, so alcohol causes acetaldehyde accumulation with flushing, nausea, vomiting and palpitations.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Fluoroquinolones such as ciprofloxacin act by inhibiting:
सही उत्तर: ख) DNA gyrase and topoisomerase IV
Fluoroquinolones inhibit bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), blocking DNA replication.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Macrolide antibiotics such as azithromycin inhibit bacterial protein synthesis by binding to the:
सही उत्तर: क) 50S ribosomal subunit
Macrolides bind the 23S rRNA of the 50S subunit and block translocation; aminoglycosides and tetracyclines act on the 30S subunit.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Vancomycin inhibits bacterial cell wall synthesis by binding to:
सही उत्तर: घ) D-alanyl-D-alanine terminus of peptidoglycan precursors
Vancomycin binds the D-Ala-D-Ala end of cell wall precursors, blocking transglycosylation; resistance (e.g. VRE) arises when this changes to D-Ala-D-lactate.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Clavulanic acid is combined with amoxicillin because it:
सही उत्तर: ग) Inhibits bacterial β-lactamases
Clavulanic acid is a β-lactamase inhibitor that protects amoxicillin from enzymatic destruction, extending its spectrum.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Ketamine produces dissociative anaesthesia mainly by blocking:
सही उत्तर: क) NMDA glutamate receptors
Ketamine is a non-competitive NMDA receptor antagonist that produces analgesia and dissociation while largely preserving airway reflexes and blood pressure.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Pulmonary fibrosis, thyroid dysfunction and corneal microdeposits are adverse effects of:
सही उत्तर: ग) Amiodarone
Amiodarone is iodine-rich and lipophilic; it can cause pulmonary fibrosis, hypo- or hyperthyroidism, corneal deposits, photosensitivity and hepatotoxicity.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Phocomelia in babies exposed in utero is the classic teratogenic effect of:
सही उत्तर: घ) Thalidomide
Thalidomide taken in early pregnancy caused limb reduction defects (phocomelia), leading to modern drug regulation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
-
Loop diuretics such as furosemide act by inhibiting the:
सही उत्तर: ख) Na⁺–K⁺–2Cl⁻ cotransporter in the thick ascending limb
Furosemide blocks NKCC2 in the thick ascending limb of the loop of Henle; thiazides block the Na⁺–Cl⁻ cotransporter in the DCT.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
नमस्ते! पाठ्यक्रम, सामान्य ज्ञान, भाषा परीक्षा वा कुनै प्रश्नको उत्तर बुझ्न सोध्नुहोस्।
AI ले गल्ती गर्न सक्छ। महत्वपूर्ण कुरा आधिकारिक स्रोतमा जाँच्नुहोस्।