फार्माकोलोजी – Pharmacology MCQ
फार्माकोलोजी – अन्तर्राष्ट्रिय नर्सिङ
Pharmacology · International Nursing (NCLEX-RN, DHA, HAAD) · ४०८ प्रश्न
४०८ प्रश्न उपलब्ध। मोड छान्नुहोस्:
फार्माकोलोजी: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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A patient receiving intravenous heparin requires careful monitoring. The nurse understands that a key indicator of therapeutic efficacy and potential complications is assessing the patient's coagulation profile. When should a trough level of an IV antibiotic be drawn?
सही उत्तर: ग) C) Before each dose of heparin, particularly if the patient experiences bruising or bleeding.
Option C is correct. A trough level represents the lowest concentration of heparin in the blood and is best assessed before each dose to ensure therapeutic anticoagulation while minimizing the risk of excessive bleeding. Options A, B, and D are less relevant to monitoring efficacy.”} , 2024){{
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient diagnosed with tuberculosis (TB) is prescribed rifampin. Which laboratory test should the nurse routinely monitor to assess for potential liver toxicity?
सही उत्तर: ख) B) Liver Function Tests (LFTs), specifically bilirubin and transaminases.
Option B is correct. Rifampin is known to cause hepatotoxicity. Regular monitoring of LFTs is crucial for early detection. CBC and urinalysis are not routinely associated with rifampicin side effects. Serum electrolytes are generally monitored as part of routine assessment.”} , 2024){{
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient is prescribed amoxicillin/clavulanate for a bacterial infection. The healthcare provider specifically advises the patient to take the medication with food. Why is this recommendation made?
सही उत्तर: क) A) To enhance the absorption of the clavulanic acid component of the drug.
Option A is correct. Amoxicillin has poor bioavailability and is better absorbed when taken with food. The clavulanic acid component is a beta-lactamase inhibitor that degrades quickly in the stomach without food. Options B, C, and D are incorrect; while food intake can reduce nausea, it’s primarily about absorption, not irritation or elimination.”} , 2024 )){{
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient is prescribed phenytoin for seizure control. Which laboratory test should be monitored regularly to assess for potential toxicity?
सही उत्तर: घ) Liver Function Tests
Phenytoin toxicity can manifest with neurological symptoms and blood abnormalities. Monitoring the serum phenytoin level is critical for determining appropriate dosing and preventing toxic effects. While other tests are important, phenytoin levels directly reflect drug accumulation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which drug classification is MOST likely to cause QT prolongation and subsequent cardiac arrhythmias?
सही उत्तर: क) ACE inhibitors
Certain medications, particularly some calcium channel blockers and macrolide antibiotics, can prolong the QT interval on an electrocardiogram. This increases the risk of ventricular arrhythmias. ACE inhibitors and NSAIDS typically have minimal impact on QT prolongation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient taking warfarin (Coumadin) reports intermittent nosebleeds. What pharmacological effect of warfarin should be considered as the most likely cause?
सही उत्तर: ख) Decreased clotting factor synthesis
Warfarin inhibits vitamin K-dependent coagulation factors, leading to a decreased ability for blood clot formation. This can manifest as bleeding tendencies such as nosebleeds.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following statements BEST describes the mechanism of action of metformin in treating type 2 diabetes?
सही उत्तर: ख) Decreases hepatic glucose production
Metformin works primarily by decreasing hepatic glucose production, which is a key factor in managing type 2 diabetes. While it does have some effects on peripheral glucose uptake, its primary action is reducing glucose output from the liver.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following medications is MOST appropriate for treating acute asthma exacerbation?
सही उत्तर: ग) C) Albuterol (nebulized)
Albuterol is a short-acting beta-agonist that quickly relaxes airway smooth muscle, providing rapid relief from bronchospasm during an acute asthma attack. Prednisone is an anti-inflammatory but slower acting than Albuterol. Montelukast is a leukotriene receptor antagonist that's more preventative. Theophylline has longer onset and higher risk of side effects.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient receiving intravenous morphine for pain is exhibiting respiratory depression. Which intervention should the nurse implement FIRST?
सही उत्तर: ख) B) Administer naloxone (Narcan).
Naloxone is an opioid antagonist that rapidly reverses the effects of opioids and counteracts respiratory depression. Administering naloxone (Option B) is the immediate priority in this situation. Increasing the morphine rate (Option A) would worsen respiratory depression, elevating the head of the bed does not directly address respiratory depression, and notifying the physician is a subsequent step.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient receiving intravenous heparin develops signs of bleeding. Which laboratory test should be performed *immediately* to determine the cause and guide treatment?
सही उत्तर: ग) C) Coagulation studies, including a PT/INR and PTT.
Option (2) is correct. Coagulation studies, particularly the PTT (partial thromboplastin time), are most sensitive to heparin's anticoagulant effects. A prolonged PTT indicates excessive heparin activity. (A) provides a general picture of blood cells but doesn’t directly measure the effect of heparin. (B) and (D) are relevant in other bleeding situations, but aren’t the priority for heparin overdose.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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