फार्माकोलोजी – Pharmacology MCQ
फार्माकोलोजी – अन्तर्राष्ट्रिय नर्सिङ
Pharmacology · International Nursing (NCLEX-RN, DHA, HAAD) · ४०८ प्रश्न
४०८ प्रश्न उपलब्ध। मोड छान्नुहोस्:
फार्माकोलोजी: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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A patient is prescribed a medication that contains an enteric coating. Why is it crucial to avoid crushing or chewing the tablet before ingestion?
सही उत्तर: ग) C) The enteric coating shields the drug from degradation by stomach acid and digestive enzymes.
Option (2) is correct. Enteric coatings are designed to resist dissolution in the acidic environment of the stomach, protecting the drug itself from breakdown while allowing it to dissolve and be absorbed in the more alkaline environment of the small intestine. Option (A) describes protection for the stomach, not the drug; (B) is incorrect about the mechanism; (D) is a potential side effect, but not the primary reason.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with symptoms of edema and requires diuretic therapy. The physician orders furosemide. Which time of day would be most appropriate to administer this medication to minimize the risk of electrolyte imbalances?
सही उत्तर: घ) D) Midday, six hours after breakfast.
Option (3) is correct. Furosemide's action is significantly influenced by food intake. Taking it 2-3 hours after a meal reduces the likelihood of GI absorption and subsequent electrolyte shifts—specifically potassium loss—which are common side effects of this drug. Option (A) increases risk, (B) could cause dehydration with diuretic effect, (D) might be too late for full effect.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient with chronic obstructive pulmonary disease (COPD) is prescribed a long-acting beta2 agonist inhaler (LABA) and a long-acting muscarinic antagonist (LAMA) inhaler. Which of the following statements best explains the rationale for using both medications simultaneously?
सही उत्तर: ख) B) Both medications work synergistically to dilate the bronchioles and improve airflow.
The correct answer is (1). LABAs relax bronchial smooth muscles, increasing airflow, while LAMAs block muscarinic receptors that constrict airways. The combination provides more effective bronchodilation and improved airflow than either medication alone. Option (A) is incorrect because mucociliary clearance is primarily related to cilia function, not LABAs. Option (C) describes separate mechanisms; option (D) misattributes the effect of LABAs.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient with asthma is prescribed a combination of Albuterol and Fluticasone via metered-dose inhaler. What is the primary purpose of Fluticasone in this regimen?
सही उत्तर: ख) To reduce airway inflammation
Fluticasone (option 1) is a corticosteroid, which is used for its anti-inflammatory effects. It targets the underlying cause of asthma symptoms – airway inflammation – whereas albuterol provides quick relief by relaxing smooth muscles. The other options describe functions of different medication classes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient is being treated for atrial fibrillation with intravenous Adenosine. Which of the following findings would indicate a successful intervention?
सही उत्तर: ग) Conversion to sinus rhythm with temporary P waves
Adenosine (option 2) works by transiently slowing conduction through the AV node, often converting atrial fibrillation to sinus rhythm. Temporary P waves indicate successful reversion to normal heart rhythm. The other options represent adverse reactions or unsuccessful treatment.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient with chronic systolic heart failure is prescribed Furosemide. Which electrolyte imbalance should the nurse monitor for as a priority?
सही उत्तर: क) Hypokalemia
Furosemide (option 0) is a loop diuretic that promotes sodium and water excretion, frequently leading to hypokalemia (low potassium levels). While other electrolyte imbalances can occur with diuretics, potassium depletion is the most immediate and critical concern. The other options are less commonly associated with this specific medication.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient is prescribed intravenous Vancomycin for suspected bacterial sepsis. Which adverse effect should the nurse monitor for most closely?
सही उत्तर: ख) Renal impairment
Renal impairment (option 1) is a well-documented and significant dose-limiting toxicity associated with prolonged Vancomycin use, particularly at high doses. The other options are less commonly directly linked to Vancomycin administration; while arrhythmias can occur in sepsis, they aren’t specifically tied to the drug itself.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following adverse effects is MOST commonly associated with prolonged use of beta-blockers?
सही उत्तर: घ) Peripheral edema and fatigue.
While beta-blockers can sometimes cause bradycardia, peripheral edema (swelling in the extremities) is a more prevalent and common adverse effect resulting from their impact on vascular smooth muscle. Options A and B represent less frequent side effects, and C isn’t typical.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient taking a diuretic medication reports excessive thirst and frequent urination. This symptom is MOST likely due to which physiological effect?
सही उत्तर: ख) Decreased antidiuretic hormone (ADH) production.
Diuretics, particularly thiazide diuretics, can lead to increased water reabsorption by decreasing the release of ADH from the posterior pituitary gland. This results in greater fluid volume and subsequent thirst and urination. Options A, B, and C describe other potential effects related to electrolyte imbalances or kidney function.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient with type 2 diabetes has been prescribed metformin. Which statement best describes a key mechanism of action for this drug?
सही उत्तर: ग) It increases the amount of glucose produced by the liver.
Metformin primarily works by improving the body’s sensitivity to insulin, which allows cells to better utilize glucose. Option A is incorrect as metformin doesn't stimulate insulin release. Options B and C are inaccurate descriptions of the drug’s effect.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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