आधारभूत विज्ञान (Anatomy, Physiology, Biochemistry) – Basic Sciences MCQ
आधारभूत विज्ञान (Anatomy, Physiology, Biochemistry) – MD/MS प्रवेश
Basic Sciences · MECEE-PG – MD/MS/MDS Entrance · ४३३ प्रश्न
४३३ प्रश्न उपलब्ध। मोड छान्नुहोस्:
आधारभूत विज्ञान (Anatomy, Physiology, Biochemistry): प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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A patient presents with symptoms consistent with classical phenylketonuria (PKU). Which enzymatic deficiency is most directly implicated in this condition?
सही उत्तर: ग) Phenylalanine hydroxylase
The correct answer is 2. Classical PKU is caused by a genetic defect in the phenylalanine hydroxylase enzyme, which is essential for converting phenylalanine to tyrosine. This leads to a buildup of phenylalanine in the blood and tissues, causing neurological damage if untreated. The other enzymes listed are involved in different metabolic pathways.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the role of the 'funny current' (If) within the SA node’s cardiac conduction system?
सही उत्तर: घ) It is responsible for the rapid depolarization during sinoatrial node activation
The correct answer is 3. The 'funny current' (If) is a unique inward sodium current that opens spontaneously in the SA node cells, establishing a slow diastolic depolarization – the initial trigger for each heartbeat. This is why it’s named ‘funny’. The other options describe different aspects of cardiac electrophysiology, but not the fundamental mechanism initiated by If.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Antidiuretic hormone (ADH) primarily regulates water reabsorption in the collecting duct through its action on which specific receptors?
सही उत्तर: ख) Vasopressin receptors
The correct answer is 1. ADH, also known as vasopressin, binds to V2 receptors located in the principal cells of the collecting duct. This binding stimulates the insertion of aquaporins, facilitating water movement into the medullary interstitium and thus increasing water reabsorption. The other options represent different hormones with distinct roles in fluid balance – aldosterone regulates sodium reabsorption, angiotensin II contributes to vasoconstriction and sodium retention, and atrial natriuretic peptide promotes sodium excretion.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following amino acids is considered a precursor for neurotransmitter synthesis (specifically dopamine)?
सही उत्तर: घ) D) Glutamine
Tyrosine is a key precursor in the biosynthesis of several important neurotransmitters, including dopamine. Valine and leucine are branched-chain amino acids primarily involved in protein synthesis. Glutamine plays other roles but isn't a direct dopamine precursor.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The presence of elevated levels of serum amylase would most likely indicate damage to which organ?
सही उत्तर: ख) B) Pancreas
Amylase is an enzyme primarily produced by the pancreas. Elevated levels in the blood typically signal pancreatic inflammation or injury, such as pancreatitis. Options A, C, and D relate to different organs with distinct enzymes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the role of cytochrome oxidase in oxidative phosphorylation?
सही उत्तर: ग) C) It pumps protons across the inner mitochondrial membrane.
Cytochrome oxidase is the terminal enzyme in the electron transport chain, where it accepts electrons from cytochrome c and reduces oxygen to form water. This completes the cycle of oxidative phosphorylation. Options A, C, and D describe other processes within the electron transport chain.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The primary function of osteocalcin in bone remodeling is:
सही उत्तर: ग) C) Regulation of calcium concentration within the extracellular fluid.
Osteocalcin, a non-collagenous protein found in bone matrix, is known for its role in stimulating osteoblast activity, leading to bone formation. This contrasts with osteoclast stimulation (option A), calcium regulation (option C), and inhibition of angiogenesis (option D).
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following statements correctly describes the function of carbonic anhydrase?
सही उत्तर: ख) B) Facilitates the conversion of carbon dioxide and water into bicarbonate ions and protons.
Carbonic anhydrase is an enzyme that catalyzes the reversible reaction between carbon dioxide and water, producing carbonic acid. This process is crucial for pH regulation and respiratory gas exchange. Option A describes glycolysis; option C relates to oxygen transport, and option D concerns collagen synthesis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The majority of red blood cells are produced in which bone marrow compartment?
सही उत्तर: क) Erythroblast compartment
The erythropoietin-stimulated erythroblast compartment is responsible for the production of the vast majority (around 95%) of red blood cells. The other options represent different cell lineages within bone marrow.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The term 'myotatic reflex' describes which physiological phenomenon?
सही उत्तर: क) Stretch reflex
A myotatic reflex involves the contraction of skeletal muscle in response to a stretch, causing an immediate increase in muscle tone. The other reflexes involve different sensory mechanisms or pathways, making ‘stretch reflex’ the accurate answer.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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