प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – Pathology, Microbiology & Pharmacology MCQ
प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – MD/MS प्रवेश
Pathology, Microbiology & Pharmacology · MECEE-PG – MD/MS/MDS Entrance · ४०८ प्रश्न
४०८ प्रश्न उपलब्ध। मोड छान्नुहोस्:
प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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A biopsy specimen from the lung shows collections of amorphous eosinophilic material surrounding blood vessels, accompanied by inflammatory cell infiltration. Which histological finding most strongly suggests a diagnosis of Pneumocystis pneumonia (PCP)?
सही उत्तर: ग) Observation of characteristic 'net-like' aggregates of yeast-like organisms
The description – amorphous eosinophilic material surrounding vessels with inflammatory cells – is classic for PCP. The ‘net-like’ aggregates of *Pneumocystis jirovecii* (formerly *Pneumocystis carinii*) are a hallmark finding in lung biopsies, confirming the diagnosis. Options 1 and 3 represent other conditions; option 2 describes pulmonary hemorrhage.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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In the context of clinical microbiology, what is the significance of a 'delicate' or ‘string test’ performed on an indole-positive bacterial culture?
सही उत्तर: क) It indicates the presence of acetoin formation and fermentation
The ‘delicate’ or ‘string test’ relies on the production of indigo dye by indole-producing bacteria. The blue color produced is a visual indicator of fermentation activity, linked to acetoin formation, which confirms indole positivity. Options 2 and 3 are incorrect. pH measurement is used for other tests.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following cellular changes is MOST consistently observed in chronic myeloid leukemia (CML)?
सही उत्तर: क) Hypercellularity of the bone marrow with small lymphocytes
CML is characterized by the Philadelphia chromosome translocation, leading to the BCR-ABL fusion gene. This drives uncontrolled proliferation of myeloid progenitor cells. Hypercellularity with specific blast features – small lymphocytes – supports this. Options 2, 3, and 4 reflect other hematological disorders.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A bacterial culture exhibits a positive catalase test. What does this indicate about the organism?
सही उत्तर: ख) The bacteria lacks enzymes to break down hydrogen peroxide
Catalase is an enzyme that breaks down hydrogen peroxide (H2O2). A positive catalase test indicates the presence of this enzyme, which is commonly found in Gram-negative bacteria. The other options relate to different bacterial characteristics or metabolic processes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the primary function of lysosomes within a eukaryotic cell?
सही उत्तर: ख) Digestion of cellular waste and debris
Lysosomes are responsible for breaking down complex molecules, including cellular waste. The other options represent functions of different organelles – protein synthesis, energy production, and gene regulation respectively. This aligns with the established role of lysosomes as the cell's ‘recycling center’.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following cellular mechanisms is primarily responsible for the anticoagulant effect of low-dose aspirin?
सही उत्तर: ख) B) Direct inhibition of thrombin synthesis.
Aspirin inhibits platelet aggregation by irreversibly blocking cyclooxygenase (COX), which reduces the formation of thromboxane A2 – a key mediator in platelet activation and aggregation. Option B describes a different mechanism, and options C and D represent alternative, less significant effects.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with jaundice, elevated liver enzymes, and a positive anti-hepatocyte cytoplasmic antigen (HCAg) antibody test. Which of the following conditions is MOST likely responsible for these findings?
सही उत्तर: ग) C) Primary Biliary Cholangitis
Autoimmune hepatitis is characterized by an autoimmune response targeting liver cells, resulting in elevated HCAg antibody levels and jaundice. While the other conditions can cause jaundice, they don’t directly correlate with the presence of anti-HCAg antibodies to this extent.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The Thiosulphate–citrate–bile salt–sucrose (TCBS) agar medium is predominantly used for the selective growth of:
सही उत्तर: ख) B) *Staphylococcus aureus*
TCBS agar is a selective medium that inhibits the growth of many common bacteria by creating conditions unfavorable for their growth, while providing nutrients and space for *Staphylococcus aureus* to thrive. Options A, C, and D are other frequently encountered bacteria that are not inhibited by this medium.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the function of epithelioid cells within a granuloma?
सही उत्तर: ख) B) They represent histiocytes derived from macrophages that have differentiated to respond to inflammatory stimuli.
Epithelioid cells are modified macrophages – specifically, they represent histiocytes derived from macrophages that have differentiated to respond to inflammatory stimuli. This response is characteristic of granulomas, and option A misattributes antibody production to these cells while options C and D relate to other cell types or processes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following statements accurately describes the clinical significance of ‘window period’ in acute Hepatitis B infection? a) It represents the time when viral load is highest. b) It is the period immediately after vaccination where protection has not yet developed. c) It's the timeframe during which detectable HBV DNA levels can fluctuate significantly, making testing unreliable for diagnosis. d) This term relates to the patient’s age range when they are most vulnerable to infection.
सही उत्तर: ग) c) It's the timeframe during which detectable HBV DNA levels can fluctuate significantly, making testing unreliable for diagnosis
The ‘window period’ in acute Hepatitis B refers to the time between exposure and the onset of detectable HBV DNA. During this period, the viral load is low but not consistently detectable by standard assays, leading to unreliable diagnostic results. Options a) and d) are incorrect as they describe different aspects of viral load or susceptibility.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
यी अभ्यास प्रश्न हुन्, आधिकारिक प्रश्न होइनन्। पाठ्यक्रम, विज्ञापन र नतिजाका लागि सम्बन्धित निकायको आधिकारिक वेबसाइट हेर्नुहोस्। उत्तरमा गल्ती भेटे प्रश्नमुनिको "टिप्पणी / गल्ती रिपोर्ट" मा लेख्नुहोस्।
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