आधारभूत विज्ञान (Anatomy, Physiology, Biochemistry) – Basic Sciences MCQ
आधारभूत विज्ञान (Anatomy, Physiology, Biochemistry) – MD/MS प्रवेश
Basic Sciences · MECEE-PG – MD/MS/MDS Entrance · ४३३ प्रश्न
४३३ प्रश्न उपलब्ध। मोड छान्नुहोस्:
आधारभूत विज्ञान (Anatomy, Physiology, Biochemistry): प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Which of the following best describes the role of interstitial fluid in maintaining homeostasis?
सही उत्तर: ख) B. It serves as a buffer, absorbing excess acid or base from surrounding tissues.
Interstitial fluid plays a crucial role in maintaining homeostasis by acting as a buffer, absorbing excess acids and bases from tissues. Option A inaccurately describes its transport functions; C misrepresents its composition, and D suggests an incorrect structural separation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The term ‘myotatone’ refers to:
सही उत्तर: क) A. The automatic muscle contraction in response to stretching.
Myotatone is the term used to describe the stretch reflex, an involuntary muscle contraction that occurs when a muscle is stretched. Option B describes voluntary movement; C and D are related to other physiological mechanisms.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following cell types primarily contributes to the formation of bone matrix during endochondral ossification?
सही उत्तर: ख) B. Chondrocytes.
Endochondral ossification begins with a cartilage model that is replaced by bone. Chondrocytes are responsible for synthesizing and maintaining the cartilaginous matrix, which is then gradually replaced by bone tissue. Osteoblasts build the new bone; fibroblasts would contribute to connective tissues and melanocytes produce pigment.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The term 'cardiac output' refers to:
सही उत्तर: ख) B. The total resistance encountered by the blood as it circulates through the cardiovascular system.
Cardiac output is calculated as Stroke Volume multiplied by Heart Rate (CO = SV x HR). Option A is a component of cardiac output, not the definition itself; B describes systemic vascular resistance; and D refers to metabolic processes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A researcher is investigating a patient's metabolism and observes elevated levels of blood sugar after consuming a carbohydrate-rich meal. Further analysis reveals that the patient’s body struggles to effectively utilize glucose. Which enzyme deficiency would MOST likely explain this clinical scenario?
सही उत्तर: घ) Phosphofructokinase
Phosphofructokinase is a key regulatory enzyme in glycolysis, the pathway for glucose breakdown. A deficiency in this enzyme directly impairs glucose metabolism and leads to elevated blood sugar levels after carbohydrate ingestion, as outlined in this scenario.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The primary metabolic defect associated with Von Gierke disease (Glycogen Storage Disease Type I) involves a deficiency in which enzyme?
सही उत्तर: ख) Glycogen phosphorylase
Von Gierke disease is caused by the deficiency of glycogen phosphorylase, the enzyme responsible for breaking down glycogen into glucose. This leads to an accumulation of glycogen in various tissues, particularly the liver. The other options represent enzymes involved in different lysosomal storage disorders.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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A patient presents with symptoms including fatigue, muscle weakness, and elevated levels of creatine kinase (CK). Biochemical analysis reveals a significantly increased serum concentration of methylmalonic acid. Which vitamin deficiency is MOST likely responsible for this condition?
सही उत्तर: ग) Vitamin B12 (Cobalamin)
Methylmalonic aciduria results from a deficiency in Vitamin B12, which acts as a cofactor for enzymes involved in the metabolism of odd-chain fatty acids and amino acids. While deficiencies in other vitamins can cause metabolic abnormalities, B12’s role directly relates to this specific symptom presentation. The other options do not typically present with methylmalonic aciduria.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following statements best describes the primary function of the glomerular capillaries in the nephron?
सही उत्तर: क) Filtration of large proteins and waste products from the blood
The glomerular capillaries are specialized for filtration. They possess pores too small for most plasma components, allowing water, electrolytes, and small solutes to pass through while retaining larger molecules like proteins. The other options describe functions of different nephron segments or metabolic processes.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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The Bohr effect demonstrates which relationship between pH and oxygen-binding affinity?
सही उत्तर: ग) C) No correlation exists between pH and oxygen binding affinity.
Option B is correct – the Bohr effect states that lower pH (higher hydrogen ion concentration) reduces the affinity of hemoglobin for oxygen, facilitating its release from the blood. Option A is incorrect; it's the reverse relationship. Options C & D are false.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Which of the following best describes the role of the epiglottis?
सही उत्तर: ख) B) To prevent food and liquids from entering the larynx during swallowing.
Option B accurately describes the epiglottis’s function – a flap of cartilage that closes over the trachea to prevent aspiration. Option A is incorrect, and Options C & D are related to other anatomical structures.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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