प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – Pathology, Microbiology & Pharmacology MCQ

प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी: प्रश्न र उत्तर

सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।

सही: ० / ०

91. The mechanism by which Linezolid inhibits bacterial protein synthesis differs from that of tetracycline antibiotics. Specifically, Linezolid acts by: a) Preventing tRNA binding to ribosomes. b) Inhibiting 30S ribosomal subunit translocation. c) Blocking the formation of the initiation complex. d) Disrupting the integrity of the bacterial cell wall.

    कa) Preventing tRNA binding to ribosomes खb) Inhibiting 30S ribosomal subunit translocation गc) Blocking the formation of the initiation complex घd) Disrupting the integrity of the bacterial cell wall
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

92. Epithelioid cells are most commonly seen in granulomas formed by the immune response to which of the following pathogens? a) *Mycobacterium tuberculosis* b) *Streptococcus pneumoniae* c) *Candida albicans* d) *Enterococcus faecalis*

    कa) *Mycobacterium tuberculosis* खb) *Streptococcus pneumoniae* गc) *Candida albicans* घd) *Enterococcus faecalis*
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

93. A patient presents with symptoms including fever, headache, and stiff neck. CSF analysis reveals numerous neutrophils and cryptococcal polysaccharide antigens. Which fungal pathogen is most likely responsible for this clinical presentation?

    क*Candida albicans* ख*Aspergillus fumigatus* ग*Cryptococcus neoformans* घ*Mucor species*
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

94. A biopsy specimen from a patient diagnosed with tuberculosis shows the presence of multinucleated giant cells engulfing macrophages and cellular debris. Which characteristic is MOST indicative of this finding?

    कGranuloma formation खLymphocytic infiltration गFocal necrosis घSeptal collapse
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

95. A patient presents with severe diarrhea, abdominal cramps, and fever following antibiotic treatment with ampicillin. Microscopic examination of the stool reveals numerous motile flagellated bacteria. The most likely causative agent is:

    क*Escherichia coli* ख*Salmonella enterica* ग*Shigella dysenteriae* घ*Clostridium difficile*
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

96. Which of the following immunological mechanisms is primarily associated with the development of erythema multiforme due to *Clostridium difficile* infection?

    कType I Hypersensitivity खType II Hypersensitivity गType III Hypersensitivity घType IV Hypersensitivity
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

97. The characteristic ‘railroad track’ appearance observed in fungal infections due to the branching hyphae is primarily associated with which type of fungi?

    कAspergillus species खPenicillium species गMucor species घCandida species
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

98. Which cellular structure is most critical for initiating the extrinsic pathway of apoptosis when activated by death receptors? (A) Mitochondria (B) Endoplasmic reticulum (C) Death-associated protein kinase (DAPK) (D) Fas receptor

    कMitochondria खEndoplasmic reticulum गDeath-associated protein kinase (DAPK) घFas receptor
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

99. A patient presents with severe thrombocytopenia following chemotherapy. Pathologically, which finding would MOST likely be observed in their bone marrow? (A) Increased megakaryocytes (B) Decreased myeloid cells with normal megakaryocyte numbers (C) Hypercellularity with prominent erythroid hyperplasia (D) Extramedullary hematopoiesis

    कIncreased megakaryocytes खDecreased myeloid cells with normal megakaryocyte numbers गHypercellularity with prominent erythroid hyperplasia घExtramedullary hematopoiesis
    💬 टिप्पणी / गल्ती रिपोर्ट (०)

    छलफल / प्रश्न उत्तरमा गल्ती छ

    पठाउनुहोस्

    टिप्पणी जाँचपछि मात्र देखिन्छ।

100. In the context of pharmacology, which mechanism primarily contributes to the observed dose-related cardiomyopathy associated with certain beta-blockers? (A) Inhibition of adrenergic receptors (B) Direct myocardial toxicity (C) Interference with mitochondrial function leading to oxidative stress (D) Stimulation of vasoconstriction

     कInhibition of adrenergic receptors खDirect myocardial toxicity गInterference with mitochondrial function leading to oxidative stress घStimulation of vasoconstriction
     💬 टिप्पणी / गल्ती रिपोर्ट (०)

     छलफल / प्रश्न उत्तरमा गल्ती छ

     पठाउनुहोस्

     टिप्पणी जाँचपछि मात्र देखिन्छ।