प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – Pathology, Microbiology & Pharmacology MCQ
प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी – MD/MS प्रवेश
Pathology, Microbiology & Pharmacology · MECEE-PG – MD/MS/MDS Entrance · ४०८ प्रश्न
४०८ प्रश्न उपलब्ध। मोड छान्नुहोस्:
प्याथोलोजी, माइक्रोबायोलोजी र फार्माकोलोजी: प्रश्न र उत्तर
सही लागेको विकल्पमा थिच्नुहोस्। सही भए हरियो, गलत भए रातो देखिन्छ; ३ सेकेन्डपछि सही उत्तर र व्याख्या देखिन्छ।
सही: ० / ०
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Mallory–Denk bodies (Mallory hyaline) in hepatocytes are composed of:
सही उत्तर: घ) Damaged intermediate filaments (cytokeratin)
Mallory–Denk bodies are eosinophilic aggregates of ubiquitinated cytokeratin, typically seen in alcoholic hepatitis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Aschoff bodies with Anitschkow ('caterpillar') cells are pathognomonic of:
सही उत्तर: क) Acute rheumatic carditis
Aschoff bodies are foci of fibrinoid change with lymphocytes and Anitschkow cells, found in all layers of the heart in rheumatic fever.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Crescent formation in most glomeruli on renal biopsy is the hallmark of:
सही उत्तर: ग) Rapidly progressive glomerulonephritis
Crescents form from proliferating parietal epithelial cells and macrophages in Bowman's space, the morphological hallmark of rapidly progressive (crescentic) GN.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Nodular glomerulosclerosis (Kimmelstiel–Wilson lesions) is characteristic of:
सही उत्तर: ख) Diabetic nephropathy
Kimmelstiel–Wilson nodules are PAS-positive mesangial nodules that are pathognomonic of diabetic glomerulosclerosis.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Teardrop cells (dacrocytes) with a leucoerythroblastic blood picture and a 'dry tap' on marrow aspiration suggest:
सही उत्तर: ख) Primary myelofibrosis
Marrow fibrosis causes extramedullary haematopoiesis, teardrop cells, leucoerythroblastosis and failed (dry) aspiration.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Schistocytes (fragmented red cells) on a blood film are a feature of:
सही उत्तर: ग) Microangiopathic haemolytic anaemia
Red cells are sheared by fibrin strands in small vessels in conditions such as DIC, TTP and haemolytic uraemic syndrome.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Howell–Jolly bodies in red cells on a peripheral smear suggest:
सही उत्तर: क) Splenectomy or functional asplenia
Howell–Jolly bodies are nuclear remnants normally removed by the spleen; they persist after splenectomy or in hyposplenism (e.g. sickle cell disease).
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Keratin pearls and intercellular bridges on histology indicate a tumour of which type?
सही उत्तर: घ) Squamous cell carcinoma
Keratinisation (keratin pearls) and desmosomal intercellular bridges are the hallmarks of squamous differentiation.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Psammoma bodies are characteristically seen in:
सही उत्तर: घ) Papillary carcinoma of the thyroid
Psammoma bodies (laminated calcified concretions) occur in papillary thyroid carcinoma, serous ovarian tumours, meningioma and mesothelioma.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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Li–Fraumeni syndrome, with sarcomas, breast cancer, brain tumours and leukaemia at a young age, is due to a germline mutation of:
सही उत्तर: क) TP53
Li–Fraumeni syndrome results from an inherited TP53 mutation, conferring a very high lifetime risk of multiple cancers.
💬 टिप्पणी / गल्ती रिपोर्ट (०)
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